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FRANCHISE STRATEGY:
From defining a vision to completing a major acquisition, Health Advances assisted our client at every step in building a formidable CNS franchise.
SITUATION
- A multi-national pharmaceutical company had recently identified CNS as a strategic focus
area to drive growth.
- With only a handful of marketed assets, the existing CNS division needed to articulate a
strategy for building a strong, competitive CNS franchise, prioritize new indications, and
implement an action plan to meet corporate goals.
CRITICAL QUESTIONS TO ADDRESS
- What is the client’s long-term vision for the CNS franchise?
- How should the company develop the franchise: through organic growth, licensing, or
acquisitions?
- How have other companies built CNS franchises, and what can be learned from them?
- Which therapeutic areas will add the most value to the company?
- Are there indications which should be avoided due to low unmet need, low pipeline quality,
or high barriers to development?
HEALTH ADVANCES APPROACH
- Profiled leading CNS franchises to reveal areas of investment and drivers of growth to
serve as examples for the client’s CNS franchise vision.
- Thoroughly reviewed clinical, scientific, and market literature to determine market
sizes/potential and unmet needs, and to identify emerging theories into the mechanisms of
fifteen CNS diseases.
- Prioritized therapeutic areas with a high degree of untapped potential and capacity
for near-term to mid-term growth.
- Identified potential acquisition targets in the development pipeline and classified
them based on stage, efficacy, and mechanism of action.
- Interviewed thought leaders with both clinical and research expertise to test the
potential value of drug candidates in each high-priority indication.
RESULTS
- Worked with a client team to establish a vision and strategy for the CNS franchise
and used it as a framework to guide business development into new indications.
- Recommended a staged approach to building the franchise with milestones related to
implementation, portfolio expansion, and market presence.
- Assisted in due diligence for partnering with another company with multiple
assets in a high-priority indication.

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