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Applications for an Antimicrobial Product: An early-stage client recognized that an antimicrobial industrial product may possess valuable
healthcare capabilities. Health Advances evaluated thirteen applications ranging from oral mucositis to onychomycosis. The evaluation included understanding
the role of pathogens, unmet needs, and developmental requirements. Using this analysis, Health Advances developed a blueprint for the client's healthcare
enterprise, which led the client's Board to appropriate several hundreds of thousands of dollars for preclinical work.
Identification and Prioritization of Target Medical Devices for a Novel Antimicrobial Coating: A large public client was committed to
developing an antimicrobial coating for a broad range of devices. Health Advances initially evaluated dozens of conceivable applications, from coatings
on disposable diapers to heart valves. The analysis quickly focused on four applications and these were then further prioritized based upon manufacturability,
clinicians' perceptions of the devices' roles in the infection process, and the value-based premiums that each could capture. The initially targeted product
has been successfully commercialized and the organization is now working on expanding the core technology and base product into a wide range of related products
for analogous indications.
Genomic-Based Infection Detection: With the goal of rapid diagnosis of infectious agents in the hospital setting, our client developed a novel
DNA-based bacterial fingerprint system. Health Advances conducted an extensive interview program with hospitals and infectious disease experts to understand
how they diagnose and treat many of the major infections seen in the hospital setting. We worked with the client to determine the value of a rapid test from
a clinical and economic perspective.
Market Assessment for a Novel Antibiotic Therapy: Health Advances worked with a private early-stage company focused on developing novel
antibiotics using structure-based design. We help our client to identify potentially attractive market opportunities in the hospital and community setting
based on unmet needs, market size, and segmentation of the current antibiotic market, antibiotics in the clinical pipeline, anticipated treatment trends,
and hospital formulary decisions.
HIV Vaccine Development Planning: Health Advances was asked to take a top-level look at a client's HIV vaccine program as part of a
company-wide portfolio reassessment initiated when a new president was appointed to the company. This review examined the client's technical progress
versus that of competitors, funding sources, likely continued commitments from those sources, and synergy with the company's other products in
development.
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