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Case Examples of Our Work with Respiratory Conditions
Therapeutic for Ventilator-Associated Pneumonia (VAP): A client with strong anti-infective science was considering developing a new agent for this indication. The Health Advances team focused on quantifying the potential size of the problem in the US and in three major European countries, since this market was not well documented in the literature and consisted of patients with a variety of underlying conditions. This study also provided insights into the current treatment for these patients and any other unmet needs, as well as competitive efforts focused on the same indication. The contributions of the Health Advances team helped the client understand the relative importance of this internal development initiative.

Pseudomonas in Cystic Fibrosis: Health Advances developed the marketing strategy for a new formulation of tobramycin for use in cystic fibrosis patients. Our work involved projecting market demand, looking at patient segmentation, analyzing pricing options, and determining the positioning for the product.

Valuation of Respiratory Indications: Health Advance assisted a large public company in the evaluation of potential lead indications for their respiratory program. Indications examined included ARDS, cystic fibrosis, COPD, nosocomial pneumonia, fungal pneumonia, ventilator acquired pneumonia, tuberculosis, and interstitial lung disease.

Hospital Respiratory Products: Health Advances assisted a major manufacturer of respiratory products in building a five-year revenue forecast for its hospital products division. The model encompassed revenue projections for the US and international markets for various hospital product lines: acute, subacute and transport invasive and non-invasive ventilation, cardiac output and vCO2 monitors, oximetry, capnography, multiparameter monitors, OEM manufacturing and disposables where relevant.

Due Diligence for a Respiratory Device Company: Health Advances performed due diligence on a company that manufactured respiratory devices used in critical care, emergency rooms, ambulances, long-term care facilities, and home care. Focus was on humidification products used in ventilation, but we also looked at ET tubes, spirometers, and nebulizers. Market growth trends in the US, UK, France and Germany were studied.

Portable Liquid Oxygen: A manufacturer of medical devices asked Health Advances to assess the US safety history of portable liquid oxygen and high-pressure tanks used for home oxygen therapy. Using secondary sources, we estimated the frequency of accidents relative to consumption. In addition, we summarized causes listed in the database and interviewed regulatory as well as home oxygen therapy experts.
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